Benoxinate-Fluorescein Ophthalmic: Side Effects, Uses, Dosage, Interactions, Warnings (2024)

• Uses
  • What Is Benoxinate-Fluorescein Ophthalmic and How Does It Work?
• Side Effects
  • What Are Side Effects Associated with Using Benoxinate-Fluorescein Ophthalmic?
• Dosages
  • What Are the Dosages of Benoxinate-Fluorescein Ophthalmic?
• Drug Interactions
  • What Other Drugs Interact with Benoxinate-Fluorescein Ophthalmic?
• Warnings and Precautions
  • What Are the Warnings and Precautions for Benoxinate-Fluorescein Ophthalmic?

What Is Benoxinate-Fluorescein Ophthalmic and How Does It Work?

Benoxinate-Fluorescein Ophthalmic is a sterile ophthalmic solution combining a disclosing agent with an anesthetic agent used for eye procedures requiring a disclosing agent in combination with an anesthetic agent such as tonometry, gonioscopy, removal of corneal foreign bodies and other short corneal or conjunctival procedures.

• Benoxinate-Fluorescein Ophthalmic is available under the following different brand names: Fluress, Fluorox

What Are Side Effects Associated with Using Benoxinate-Fluorescein Ophthalmic?

Common side effects of Benoxinate-Fluorescein Ophthalmic include:

• temporary stinging and burning in the treated eye
• eye irritation
• conjunctival redness
• contact dermatitis on fingertips
• allergic reaction (rare)

Serious side effects of Benoxinate-Fluorescein Ophthalmic include:

• hives
• difficulty breathing
• swelling of the face, lips, tongue, or throat
• feeling like there is something in your eye
• watery eyes or increased tearing eye
• changes in your vision
• stinging or burning in the eye
• redness of the eye
• swollen eyelids

Rare side effects of Benoxinate-Fluorescein Ophthalmic include:

• none

Seek medical care or call 911 at once if you have the following serious side effects:

• Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, coordination loss, unsteady, very stiff muscles, high fever, profuse sweating, or tremors
• Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights
• Serious heart symptoms include fast, irregular, or pounding heartbeats; fluttering in the chest; shortness of breath; sudden dizziness, lightheadedness, or passing out

This is not a complete list of side effects and other serious side effects or health problems that may occur because of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems toFDAat 1-800-FDA-1088.

What Are the Dosages of Benoxinate-Fluorescein Ophthalmic?

Adult dosage

Ophthalmic solution

• 0.4%/0.25%

Removal of foreign bodies, sutures, or tonometry

Adult dosage

• 1-2 drops into each eye before the procedure

Deep ophthalmic anesthesia

Adult dosage

• 2 drops in each eye every 90 seconds for 3 doses

Dosage Considerations – Should be Given as Follows:

• See “Dosages”

What Other Drugs Interact with Benoxinate-Fluorescein Ophthalmic?

If your medical doctor is using this medicine to treat your pain, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them.Do not start, stop, or change the dosage of any medicine before checking with your doctor, healthcare provider, or pharmacist first.

• Benoxinate-Fluorescein Ophthalmic has no noted severe interactions with any other drugs
• Benoxinate-Fluorescein Ophthalmic has no noted serious interactions with any other drugs
• Benoxinate-Fluorescein Ophthalmic has no noted moderate interactions with any other drugs
• Benoxinate-Fluorescein Ophthalmic has no noted minor interactions with any other drugs

This information does not contain all possible interactions or adverse effects. Visit the RxList Drug Interaction Checker for any drug interactions. Therefore, before using this product, tell your doctor or pharmacist about all the products you use. Keep a list of all your medications with you and share this information with your doctor and pharmacist. Check with your healthcare professional or doctor for additional medical advice, health questions, or concerns.

What Are the Warnings and Precautions for Benoxinate-Fluorescein Ophthalmic?

Contraindications

• Hypersensitivity to either component or similar drugs

Effects of drug abuse

• None

Short-Term Effects

• See “What Are Side Effects Associated with Using Benoxinate-Fluorescein Ophthalmic?”

Long-Term Effects

• See “What Are Side Effects Associated with Using Benoxinate-Fluorescein Ophthalmic?”

Cautions

• Prolonged use is not recommended as it may diminish the duration of anesthesia, retard wound healing, and cause corneal infection and/or opacification with accompanying permanent visual loss or corneal perforation
• Systemic toxicity (CNS stimulation followed by CNS and cardiovascular depression) is possible but rare
• Protection of the eye from other irritating chemicals, foreign bodies, and rubbing during the period of anesthesia is very important
• CNS stimulation followed by depression may occur with topical application of local anesthetics
• Use cautiously and sparingly in patients with known allergies, cardiac disease, or hyperthyroidism

Pregnancy and Lactation

• Use with caution if the benefits outweigh the risks during pregnancy
• Lactation
  • Unknown whether distributed in breast milk; caution advised